Uveo Dermatological Syndrome (vogt-koyanagi- Harada-like Syndrome) with Depigmentation in a Labrador Retriever Dog: a Case Report

A 4 year old female Labrador retriever was presented with a history of visual deficit for the past 3 months. A detailed ophthalmic examination with a direct and indirect ophthalmoscope revealed, sluggish PLR, shallow anterior chamber and irregular pupillary border and bilateral uveitis. There was progressive depigmentation of the retinal pigment epithelium in the nontapetal area, tapetal hyperreflectivity and attenuation of the retinal blood vessels. Based on a combination of the ocular and dermatologic lesions it is diagnosed as Uveo Dermatological Syndrome. Medical treatment was initiated with oral glucocorticoids and immune suppressant drugs azathioprine. Both dermatologic and ophthalmic signs showed good improvement, vision was preserved, and some repigmentation of the skin and hair occurred and uneventful recovery was noticed.